Alkyl Halides
Medchemexpress LLC Beperidium iodide | 86434-57-3 | MFCD00866899 | 100.0% | 527.44 g/mol | C23H34IN3O3 | 5 MG
Beperidium iodide is the iodide salt of a bioactive compound used as a competitive antagonist of acetylcholine receptors. It is supplied as a small, high-purity research reagent with a reported pA2 of 7.93, intended for use as a pharmacological probe in studies of cholinergic signaling.
- Competitive antagonist of acetylcholine receptors with reported pA2 = 7.93.
- High purity (99.97%) suitable for analytical and experimental use.
- Molecular formula C23H34IN3O3 and molecular weight 527.44 g/mol.
- Available as a 5 mg research pack for laboratory studies.
- Provided as the iodide salt for improved stability and handling.
Medchemexpress LLC Bay-593 | 2413020-56-9 | 99.9% | 476.53 | 100 MG
BAY-593 is an orally active GGTase-I inhibitor that can block YAP1/TAZ signaling in animals and exhibits antitumor activity.
- Orally active GGTase-I inhibitor
- Blocks YAP1/TAZ signaling in animals
- Shows antitumor activity
eMolecules AstaTech / BIS(TRICYCLOHEXYLPHOSPHINE)PALLADIUM(0) / 0.25g / 696744802 / E73869 / 95.000 / 33309-88-5 / MFCD01073796 / 667.290 / C36H66P2Pd
AstaTech / BIS(TRICYCLOHEXYLPHOSPHINE)PALLADIUM(0) / 0.25g / 696744802 / E73869 / 95.000 / 33309-88-5 / MFCD01073796 / 667.290 / C36H66P2Pd
Medchemexpress LLC MPP+ iodide | 36913-39-0 | 100.0% | 297.14 | 50 MG
MPP+ iodide is a toxic metabolite of the neurotoxin MPTP. It causes symptoms of Parkinson's disease in animal models by selectively destroying dopaminergic neurons in the substantia nigra. It is taken up by the dopamine transporter into dopaminergic neurons, where it exerts its neurotoxic action on mitochondria by affecting complex I of the respiratory chain. MPP+ iodide is also a high-affinity substrate for the serotonin transporter (SERT).
- Toxic metabolite of neurotoxin MPTP.
- Causes Parkinson's disease symptoms in animal models.
- Selectively destroys dopaminergic neurons in substantia nigra.
- Taken up by dopamine transporter into dopaminergic neurons.
- Exerts neurotoxic action on mitochondria by affecting complex I of the respiratory chain.
- High-affinity substrate for the serotonin transporter (SERT).
eMolecules AstaTech / (DIMETHYLAMINOMETHYLENE)MALONONITRILE / 1g / 449723896 / 31242 / 97.000 / 16849-88-0 / MFCD00001853 / 121.143 / C6H7N3
AstaTech / (DIMETHYLAMINOMETHYLENE)MALONONITRILE / 1g / 449723896 / 31242 / 97.000 / 16849-88-0 / MFCD00001853 / 121.143 / C6H7N3
eMolecules AstaTech / POTASSIUM PHENYL SULFATE / 0.25g / 448280741 / T71922 / 98.000 / 1733-88-6 / MFCD00070590 / 212.260 / C6H5KO4S
AstaTech / POTASSIUM PHENYL SULFATE / 0.25g / 448280741 / T71922 / 98.000 / 1733-88-6 / MFCD00070590 / 212.260 / C6H5KO4S
Medchemexpress LLC N-(4-((4-isopropylpiperazin-1-yl)sulfonylphenyl)-5-pentafluorophenyl)nicotinamide | 1803003-65-7 | 99.9% | 513.54 | 5 MG
RN-1665 is an orally active TRPV4 antagonist that exhibits excellent selectivity for related TRP receptors such as TRPV1, TRPV3, and TRPM8. RN-1665 is a TRPV4 probe for focus screens, with IC50s of 0.26 μM and 0.39 μM for hTRPV4 and rTRPV4 from human and rat, respectively.
- IC50 for human TRPV4 is 0.26 μM.
- IC50 for rat TRPV4 is 0.39 μM.
- Antagonist activity at human TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 minutes.
- Antagonist activity at rat TRPV4 receptor expressed in HEK293 cells assessed as inhibition of EC80 of 4alpha-PDD-stimulated calcium flux after 10 minutes.
- Pharmacokinetic analysis has been performed in Wistar rats.
eMolecules ChemScene / 4-Chloro-2-fluorobenzothioamide / 250mg / 572194186 / CS-0114061 / 0.000 / 1343722-88-2 / MFCD17290209 / 189.630 / C7H5ClFNS
ChemScene / 4-Chloro-2-fluorobenzothioamide / 250mg / 572194186 / CS-0114061 / 0.000 / 1343722-88-2 / MFCD17290209 / 189.630 / C7H5ClFNS
eMolecules 6,7-Dibromobenzo(1,4)dioxan | 25812-80-0 | MFCD00463506 | 1g
Combi-Blocks | 6,7-Dibromobenzo(1,4)dioxan | 1g | 117543164 | OT-1148 | 97.000 | 25812-80-0 | MFCD00463506 | 293.942 | C8H6Br2O2
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Medchemexpress LLC 1-Propanone, 3,3,3-trifluoro-2-methoxy-1-[(7R)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-, (2R)- | 2413020-56-9 | 99.9% | 476.53 | 25 MG
BAY-593 is an orally active GGTase-I inhibitor. It can block YAP1/TAZ signaling in animals and has antitumor activity.
- Orally active GGTase-I inhibitor
- Blocks YAP1/TAZ signaling in animals
- Exhibits antitumor activity
- Inhibits proliferation of HT-1080 and MDA-MB-231 cells with IC50 values of 0.038 and 0.564 μM, respectively
- Shows dose-dependent antitumor activity in HT-1080 fibrosarcoma and MDA-MB-231 triple negative breast cancer xenotransplantation mouse models
Medchemexpress LLC Methylene blue | 61-73-4 | 95.0% | C16H18ClN3S | 10 MM * 1 ML
Methylene blue is an inhibitor of guanylyl cyclase (sGC), monoamine oxidase A (MAO-A), and NO synthase (NOS). It acts as a vasopressor and is commonly used as a dye in medical procedures. This REDOX cycling compound crosses the blood-brain barrier, functions as a Tau aggregation inhibitor, and has been shown to reduce cerebral edema, attenuate microglial activation, and decrease neuroinflammation.
- Inhibits guanylyl cyclase (sGC), monoamine oxidase A (MAO-A), and NO synthase (NOS)
- Acts as a vasopressor and dye in medical procedures
- REDOX cycling compound; crosses the blood-brain barrier
- Inhibits Tau aggregation
- Reduces cerebral edema and attenuates microglial activation
- Decreases neuroinflammation
eMolecules ChemScene / 3-(2-(Difluoromethoxy)phenyl)propanoic acid / 100mg / 794193835 / CS-0365521 / 0.000 / 1017030-88-4 / MFCD09951709 / 216.184 / C10H10F2O3
ChemScene / 3-(2-(Difluoromethoxy)phenyl)propanoic acid / 100mg / 794193835 / CS-0365521 / 0.000 / 1017030-88-4 / MFCD09951709 / 216.184 / C10H10F2O3
Medchemexpress LLC Demethylzeylasteral | 107316-88-1 | 480.59 | 20 MG
Demethylzeylasteral | 107316-88-1 | 480.59 | 20 MG
eMolecules AstaTech / 5-(4-CHLOROBENZAMIDO)-2-ETHOXYBENZENE-1-SULFONYL CHLORIDE / 0.1g / 721754411 / AB1324 / 95.000 / 680617-88-3 / MFCD03424955 / 374.230 / C15H13Cl2NO4S
AstaTech / 5-(4-CHLOROBENZAMIDO)-2-ETHOXYBENZENE-1-SULFONYL CHLORIDE / 0.1g / 721754411 / AB1324 / 95.000 / 680617-88-3 / MFCD03424955 / 374.230 / C15H13Cl2NO4S